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Temperature-Sensitive Mutants of Influenza A Virus: Transfer of the Two Temperature-Sensitive Lesions in the Udorn/72-ts-1A2 Virus to the A/Hong Kong/123/77 (H1N1) Wild-Type Virus

The influenza A/Udorn/72-ts-1A2 virus possesses temperature-sensitive mutations in the genes coding for the P1 and P3 polymerase proteins. It is being evaluated as a donor of its attenuating temperature-sensitive genes to produce recombinant live vaccine strains of epidemic variants of influenza A v...

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Bibliografiset tiedot
Päätekijät: Murphy, Brian R., Hosier, Nanette T., Chanock, Robert M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1980
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC551020/
https://ncbi.nlm.nih.gov/pubmed/7399695
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