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Temperature-Sensitive Mutants of Influenza A Virus: Transfer of the Two Temperature-Sensitive Lesions in the Udorn/72-ts-1A2 Virus to the A/Hong Kong/123/77 (H1N1) Wild-Type Virus

The influenza A/Udorn/72-ts-1A2 virus possesses temperature-sensitive mutations in the genes coding for the P1 and P3 polymerase proteins. It is being evaluated as a donor of its attenuating temperature-sensitive genes to produce recombinant live vaccine strains of epidemic variants of influenza A v...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Murphy, Brian R., Hosier, Nanette T., Chanock, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1980
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC551020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7399695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.28.3.792-798.1980
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