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Temperature-Sensitive Mutants of Influenza A Virus: Evaluation of A/Victoria/3/75-ts-1[E] Recombinant Viruses in Volunteers

The Hong Kong/68-ts-1[E] virus and its Udorn/72 and Georgia/74 recombinants, which have a 38°C shutoff temperature and a ts lesion(s) on the genes coding for the P3 and NP proteins, were adequately attenuated and immunogenic in adult volunteers who lacked serum hemagglutination-inhibiting antibody (...

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Опубликовано в::Infect Immun
Главные авторы: Murphy, Brian R., Markoff, Lewis J., Hosier, Nanette T., Rusten, Harold M., Chanock, Robert M., Kendal, Alan P., Douglas, R. Gordon, Betts, Robert F., Cate, Thomas R., Couch, Robert B., Levine, Myron M., Waterman, Daniel H., Holley, H. Preston
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1978
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/669819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.20.3.671-677.1978
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