Temperature-Sensitive Mutants of Influenza A Virus: Evaluation of A/Victoria/3/75-ts-1[E] Recombinant Viruses in Volunteers

The Hong Kong/68-ts-1[E] virus and its Udorn/72 and Georgia/74 recombinants, which have a 38°C shutoff temperature and a ts lesion(s) on the genes coding for the P3 and NP proteins, were adequately attenuated and immunogenic in adult volunteers who lacked serum hemagglutination-inhibiting antibody (...

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Bibliografische gegevens
Hoofdauteurs: Murphy, Brian R., Markoff, Lewis J., Hosier, Nanette T., Rusten, Harold M., Chanock, Robert M., Kendal, Alan P., Douglas, R. Gordon, Betts, Robert F., Cate, Thomas R., Couch, Robert B., Levine, Myron M., Waterman, Daniel H., Holley, H. Preston
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1978
Onderwerpen:
Viral Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC421911/
https://ncbi.nlm.nih.gov/pubmed/669819
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