Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation

Determining the cellular level of activated form of RhoGTPases is of key importance to understand their regulatory functions in cell physiopathology. We previously reported scFvC1, that selectively bind to the GTP-bound form of RhoA, RhoB and RhoC. In this present study we generate, by molecular evo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Chinestra, Patrick, Olichon, Aurélien, Medale-Giamarchi, Claire, Lajoie-Mazenc, Isabelle, Gence, Rémi, Inard, Cyril, Ligat, Laetitia, Faye, Jean-Charles, Favre, Gilles
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218836/
https://ncbi.nlm.nih.gov/pubmed/25365345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111034
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