EG-14 EPIGENETIC DYSREGULATION OF THE HoxA LOCUS AND OTHER HOMEOBOX GENES DRIVEN BY Ink4a/arf DEFICIENCY AND EGFRviii

It is increasingly clear that while genetic alterations drive glioblastoma development, epigenetic dysregulation can also contribute to oncogenesis. Although there is clear evidence of tumors driven by specific mutations to histones or their modifiers, genomic studies have demonstrated that the majo...

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Autores principales: Salinas, Ryan, Liu, John, Delgado, Ryan, Park, Ki Youb, Price, James, Ramos, Alex, Phillips, Joanna, Lim, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218092/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou254.14
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