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The Ink4a/Arf Locus Is a Barrier to Direct Neuronal Transdifferentiation
Non-neurogenic cell types, such as cortical astroglia and fibroblasts, can be directly converted into neurons by the overexpression of defined transcription factors. Normally, the cellular phenotype of such differentiated cells is remarkably stable and resists direct cell transdifferentiation. Here...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4160784/ https://ncbi.nlm.nih.gov/pubmed/25209293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3159-13.2014 |
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