Loading...

Insights into the Gating Mechanism of the Ryanodine-Modified Human Cardiac Ca(2+)-Release Channel (Ryanodine Receptor 2)

Ryanodine receptors (RyRs) are intracellular membrane channels playing key roles in many Ca(2+) signaling pathways and, as such, are emerging novel therapeutic and insecticidal targets. RyRs are so named because they bind the plant alkaloid ryanodine with high affinity and although it is established...

Full description

Saved in:
Bibliographic Details
Main Authors: Mukherjee, Saptarshi, Thomas, N. Lowri, Williams, Alan J.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216943/
https://ncbi.nlm.nih.gov/pubmed/25002270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093757
Tags: Add Tag
No Tags, Be the first to tag this record!