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Insights into the Gating Mechanism of the Ryanodine-Modified Human Cardiac Ca(2+)-Release Channel (Ryanodine Receptor 2)
Ryanodine receptors (RyRs) are intracellular membrane channels playing key roles in many Ca(2+) signaling pathways and, as such, are emerging novel therapeutic and insecticidal targets. RyRs are so named because they bind the plant alkaloid ryanodine with high affinity and although it is established...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216943/ https://ncbi.nlm.nih.gov/pubmed/25002270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093757 |
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