Development of N-Methyl-(2-arylquinolin-4-yl)oxypropanamides as Leads to PET Radioligands for Translocator Protein (18 kDa)

[Image: see text] Translocator protein (18 kDa), known as TSPO, is a recognized biomarker of neuroinflammation. Radioligands with PET accurately quantify TSPO in neuroinflammatory conditions. However, the existence of three human TSPO genotypes that show differential affinity to almost all useful TS...

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Main Authors: Brouwer, Chad, Jenko, Kimberly, Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2014
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216211/
https://ncbi.nlm.nih.gov/pubmed/24949670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5007947
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