Amyloid-β Pathology and APOE Genotype Modulate Retinoid X Receptor Agonist Activity in Vivo

Previous data demonstrate that bexarotene (Bex), retinoid X receptor (RXR) agonist, reduces soluble and insoluble amyloid-β (Aβ) in Alzheimer disease (AD)-transgenic mice either by increasing the levels of mouse apolipoprotein E (apoE) or increasing ABCA1/ABCG1-induced apoE lipoprotein association/l...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tai, Leon M., Koster, Kevin P., Luo, Jia, Lee, Sue H., Wang, Yue-ting, Collins, Nicole C., Ben Aissa, Manel, Thatcher, Gregory R. J., LaDu, Mary Jo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215234/
https://ncbi.nlm.nih.gov/pubmed/25217640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600833
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia