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APOE genotype alters glial activation and loss of synaptic markers in mice
The E4 allele of the Apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), and affects clinical outcomes of chronic and acute brain damages. The mechanisms by which apoE affect diverse diseases and disorders may involve modulation of the glia...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276698/ https://ncbi.nlm.nih.gov/pubmed/22228589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22289 |
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