Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype

Blood-brain barrier (BBB) dysfunction might be an important component of many neurodegenerative disorders. In this study, we investigated its role in dementia using large clinical cohorts. The cerebrospinal fluid (CSF)/plasma albumin ratio (Qalb), an indicator of BBB (and blood-CSF barrier) permeabi...

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Publicado en:Neurobiol Aging
Main Authors: Janelidze, Shorena, Hertze, Joakim, Nägga, Katarina, Nilsson, Karin, Nilsson, Christer, Wennström, Malin, van Westen, Danielle, Blennow, Kaj, Zetterberg, Henrik, Hansson, Oskar
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754327/
https://ncbi.nlm.nih.gov/pubmed/28061383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.11.017
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