Pro-apoptotic BIM is an essential initiator of physiological endothelial cell death independent of regulation by FOXO3

The growth of new blood vessels by angiogenesis is essential for normal development, but can also cause or contribute to the pathology of numerous diseases. Recent studies have shown that BIM, a pro-apoptotic BCL2-family protein, is required for endothelial cell apoptosis in vivo, and can contribute...

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Autori principali: Koenig, M N, Naik, E, Rohrbeck, L, Herold, M J, Trounson, E, Bouillet, P, Thomas, T, Voss, A K, Strasser, A, Coultas, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211375/
https://ncbi.nlm.nih.gov/pubmed/24971484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.90
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