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Cellular manganese content is developmentally regulated in human dopaminergic neurons

Manganese (Mn) is both an essential biological cofactor and neurotoxicant. Disruption of Mn biology in the basal ganglia has been implicated in the pathogenesis of neurodegenerative disorders, such as parkinsonism and Huntington's disease. Handling of other essential metals (e.g. iron and zinc)...

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Autori principali: Kumar, Kevin K., Lowe, Jr., Edward W., Aboud, Asad A., Neely, M. Diana, Redha, Rey, Bauer, Joshua A., Odak, Mihir, Weaver, C. David, Meiler, Jens, Aschner, Michael, Bowman, Aaron B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210885/
https://ncbi.nlm.nih.gov/pubmed/25348053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06801
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