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Cellular manganese content is developmentally regulated in human dopaminergic neurons
Manganese (Mn) is both an essential biological cofactor and neurotoxicant. Disruption of Mn biology in the basal ganglia has been implicated in the pathogenesis of neurodegenerative disorders, such as parkinsonism and Huntington's disease. Handling of other essential metals (e.g. iron and zinc)...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210885/ https://ncbi.nlm.nih.gov/pubmed/25348053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06801 |
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