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From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Human Dopamine Neurons

Parkinson’s disease (PD) is the result of complex interactions between genetic and environmental factors. Two chemically distinct environmental stressors relevant to PD are the metal manganese and the pesticide rotenone. Both are thought to exert neurotoxicity at least in part via oxidative stress r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Sci
Hauptverfasser: Neely, M. Diana, Davison, Carrie Ann, Aschner, Michael, Bowman, Aaron B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837701/
https://ncbi.nlm.nih.gov/pubmed/28962525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx145
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