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Cellular manganese content is developmentally regulated in human dopaminergic neurons

Manganese (Mn) is both an essential biological cofactor and neurotoxicant. Disruption of Mn biology in the basal ganglia has been implicated in the pathogenesis of neurodegenerative disorders, such as parkinsonism and Huntington's disease. Handling of other essential metals (e.g. iron and zinc)...

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Detalhes bibliográficos
Main Authors: Kumar, Kevin K., Lowe, Jr., Edward W., Aboud, Asad A., Neely, M. Diana, Redha, Rey, Bauer, Joshua A., Odak, Mihir, Weaver, C. David, Meiler, Jens, Aschner, Michael, Bowman, Aaron B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210885/
https://ncbi.nlm.nih.gov/pubmed/25348053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06801
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