ACYCLOVIR IS ACTIVATED INTO A HIV-1 REVERSE TRANSCRIPTASE INHIBITOR IN HERPESVIRUS-INFECTED HUMAN TISSUES

For most viruses, including HIV, there is a need for antimicrobials that target unique viral molecular properties. Acyclovir (ACV) is such a drug for human herpesviruses (HHVs): it is activated into a HHV-DNA polymerase inhibitor exclusively by HHV-kinases and thus does not suppress other viruses. H...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lisco, Andrea, Vanpouille, Christophe, Tchesnokov, Egor P., Grivel, Jean-Charles, Biancotto, Angélique, Brichacek, Beda, Elliott, Julie, Fromentin, Emilie, Shattock, Robin, Anton, Peter, Gorelick, Robert, Balzarini, Jan, McGuigan, Christopher, Derudas, Marco, Götte, Matthias, Schinazi, Raymond F., Margolis, Leonid
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210193/
https://ncbi.nlm.nih.gov/pubmed/18779052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.07.008
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires