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Exploiting the Anti-HIV-1 Activity of Acyclovir: Suppression of Primary and Drug-Resistant HIV Isolates and Potentiation of the Activity by Ribavirin

Multiple clinical trials have demonstrated that herpes simplex virus 2 (HSV-2) suppressive therapy using acyclovir (ACV) or valacyclovir in HIV-1/HSV-2-infected persons increased the patient's survival and decreased the HIV-1 load. It has been shown that the incorporation of ACV-monophosphate i...

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Dettagli Bibliografici
Autori principali: Vanpouille, Christophe, Lisco, Andrea, Introini, Andrea, Grivel, Jean-Charles, Munawwar, Arshi, Merbah, Melanie, Schinazi, Raymond F., Derudas, Marco, McGuigan, Christopher, Balzarini, Jan, Margolis, Leonid
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346610/
https://ncbi.nlm.nih.gov/pubmed/22314523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05986-11
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