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Structural and Functional Characterization of Cleavage and Inactivation of Human Serine Protease Inhibitors by the Bacterial SPATE Protease EspPα from Enterohemorrhagic E. coli

EspPα and EspI are serine protease autotransporters found in enterohemorrhagic Escherichia coli. They both belong to the SPATE autotransporter family and are believed to contribute to pathogenicity via proteolytic cleavage and inactivation of different key host proteins during infection. Here, we de...

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書誌詳細
主要な著者: Weiss, André, Joerss, Hanna, Brockmeyer, Jens
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210187/
https://ncbi.nlm.nih.gov/pubmed/25347319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111363
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