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Serine Protease EspP from Enterohemorrhagic Escherichia Coli Is Sufficient to Induce Shiga Toxin Macropinocytosis in Intestinal Epithelium

Life-threatening intestinal and systemic effects of the Shiga toxins produced by enterohemorrhagic Escherichia coli (EHEC) require toxin uptake and transcytosis across intestinal epithelial cells. We have recently demonstrated that EHEC infection of intestinal epithelial cells stimulates toxin macro...

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Hlavní autoři: In, Julie, Lukyanenko, Valeriy, Foulke-Abel, Jennifer, Hubbard, Ann L., Delannoy, Michael, Hansen, Anne-Marie, Kaper, James B., Boisen, Nadia, Nataro, James P., Zhu, Chengru, Boedeker, Edgar C., Girón, Jorge A., Kovbasnjuk, Olga
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715455/
https://ncbi.nlm.nih.gov/pubmed/23874912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069196
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