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Serine Protease EspP from Enterohemorrhagic Escherichia Coli Is Sufficient to Induce Shiga Toxin Macropinocytosis in Intestinal Epithelium

Life-threatening intestinal and systemic effects of the Shiga toxins produced by enterohemorrhagic Escherichia coli (EHEC) require toxin uptake and transcytosis across intestinal epithelial cells. We have recently demonstrated that EHEC infection of intestinal epithelial cells stimulates toxin macro...

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Detalhes bibliográficos
Main Authors: In, Julie, Lukyanenko, Valeriy, Foulke-Abel, Jennifer, Hubbard, Ann L., Delannoy, Michael, Hansen, Anne-Marie, Kaper, James B., Boisen, Nadia, Nataro, James P., Zhu, Chengru, Boedeker, Edgar C., Girón, Jorge A., Kovbasnjuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715455/
https://ncbi.nlm.nih.gov/pubmed/23874912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069196
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