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Alternating antibiotic treatments constrain evolutionary paths to multidrug resistance
Alternating antibiotic therapy, in which pairs of drugs are cycled during treatment, has been suggested as a means to inhibit the evolution of de novo resistance while avoiding the toxicity associated with more traditional combination therapy. However, it remains unclear under which conditions and b...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210010/ https://ncbi.nlm.nih.gov/pubmed/25246554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409800111 |
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