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Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes
Predicting evolutionary paths to antibiotic resistance is key for understanding and controlling drug resistance. When considering a single final resistant genotype, epistatic contingencies among mutations restricts evolution to a small number of adaptive paths. Less attention has been given to multi...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548896/ https://ncbi.nlm.nih.gov/pubmed/26060115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8385 |
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