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Accelerated evolution of resistance in multidrug environments

The emergence of resistance during multidrug chemotherapy impedes the treatment of many human diseases, including malaria, TB, HIV, and cancer. Although certain combination therapies have long been known to be more effective in curing patients than single drugs, the impact of such treatments on the...

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Autors principals: Hegreness, Matthew, Shoresh, Noam, Damian, Doris, Hartl, Daniel, Kishony, Roy
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544564/
https://ncbi.nlm.nih.gov/pubmed/18779569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805965105
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