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Accelerated evolution of resistance in multidrug environments

The emergence of resistance during multidrug chemotherapy impedes the treatment of many human diseases, including malaria, TB, HIV, and cancer. Although certain combination therapies have long been known to be more effective in curing patients than single drugs, the impact of such treatments on the...

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Hlavní autoři: Hegreness, Matthew, Shoresh, Noam, Damian, Doris, Hartl, Daniel, Kishony, Roy
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544564/
https://ncbi.nlm.nih.gov/pubmed/18779569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805965105
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