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Accelerated evolution of resistance in multidrug environments

The emergence of resistance during multidrug chemotherapy impedes the treatment of many human diseases, including malaria, TB, HIV, and cancer. Although certain combination therapies have long been known to be more effective in curing patients than single drugs, the impact of such treatments on the...

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Autori principali: Hegreness, Matthew, Shoresh, Noam, Damian, Doris, Hartl, Daniel, Kishony, Roy
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544564/
https://ncbi.nlm.nih.gov/pubmed/18779569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805965105
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