Heterodimeric Bispecific Single-Chain Variable-Fragment Antibodies Against EpCAM and CD16 Induce Effective Antibody-Dependent Cellular Cytotoxicity Against Human Carcinoma Cells

A heterodimeric bispecific biological recombinant drug was synthesized by splicing DNA fragments from two fully humanized single-chain variable-fragment (scFV) antibody fragments forming a novel drug simultaneously recognizing the CD16 natural killer (NK) cell marker and the cancer marker epithelial...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Vallera, Daniel A., Zhang, Bin, Gleason, Michelle K., Oh, Seunguk, Weiner, Louis M., Kaufman, Dan S., McCullar, Valarie, Miller, Jeffrey S., Verneris, Michael R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2013
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209492/
https://ncbi.nlm.nih.gov/pubmed/23611188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2012.1329
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk