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Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages
Substance abuse is a risk factor for HIV infection and progression to AIDS. Recent evidence establishes that cocaine use promotes brain perivascular macrophage infiltration and microglia activation. The lysosomal protease cathepsin B is increased in monocytes from patients with HIV dementia and its...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209444/ https://ncbi.nlm.nih.gov/pubmed/25209871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9563-z |
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