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Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages

Substance abuse is a risk factor for HIV infection and progression to AIDS. Recent evidence establishes that cocaine use promotes brain perivascular macrophage infiltration and microglia activation. The lysosomal protease cathepsin B is increased in monocytes from patients with HIV dementia and its...

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書目詳細資料
Main Authors: Zenón, Frances, Segarra, Annabell C., Gonzalez, Mariangeline, Meléndez, Loyda M.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209444/
https://ncbi.nlm.nih.gov/pubmed/25209871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9563-z
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