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HIV-infected microglia mediate cathepsin B induced neurotoxicity

BACKGROUND: HIV-1-infected mononuclear phagocytes release soluble factors that affect the homeostasis in tissue. HIV-1 can prompt metabolic encephalopathy with the addition of neuronal dysfunction and apoptosis. Recently, we reported that HIV-1 enhances the expression and secretion of bioactive cath...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Zenón, Frances, Cantres-Rosario, Yisel, Adiga, Radhika, Gonzalez, Mariangeline, Rodriguez-Franco, Eillen, Langford, Dianne, Melendez, Loyda M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618197/
https://ncbi.nlm.nih.gov/pubmed/26092112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-015-0358-7
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