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Cathepsin B and cystatin B in HIV-seropositive women are associated with infection and HIV-1-associated neurocognitive disorders

OBJECTIVE: HIV-1-associated neurocognitive disorders (HAND) is triggered by immune activation of brain cells and remain prevalent during progressive viral infection despite antiretroviral therapy. Cathepsins and cystatins are lysosomal proteins secreted by macrophages and microglia, and may play imp...

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Detalhes bibliográficos
Main Authors: Cantres-Rosario, Yisel, Plaud-Valentín, Marines, Gerena, Yamil, Skolasky, Richard L., Wojna, Valerie, Meléndez, Loyda M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593054/
https://ncbi.nlm.nih.gov/pubmed/23291538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32835b3e47
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