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Selectivity and Evolutionary Divergence of Metabotropic Glutamate Receptors for Endogenous Ligands and G Proteins Coupled to Phospholipase C or TRP Channels

To define the upstream and downstream signaling specificities of metabotropic glutamate receptors (mGluR), we have examined the ability of representative mGluR of group I, II, and III to be activated by endogenous amino acids and catalyze activation of G proteins coupled to phospholipase C (PLC), or...

詳細記述

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書誌詳細
主要な著者: Kang, Hye Jin, Menlove, Kit, Ma, Jianpeng, Wilkins, Angela, Lichtarge, Olivier, Wensel, Theodore G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208005/
https://ncbi.nlm.nih.gov/pubmed/25193666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574483
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