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Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

Metformin has been a first-line treatment for type II diabetes mellitus for decades and is the most widely prescribed antidiabetic drug. Retrospective studies have found that metformin treatment is associated with both reduced cancer diagnoses and cancer-related deaths. Despite the prevalence of met...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Luengo, Alba, Sullivan, Lucas B, Heiden, Matthew G Vander
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207883/
https://ncbi.nlm.nih.gov/pubmed/25347702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0082-4
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