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Stable Cellular Senescence Is Associated with Persistent DDR Activation
The DNA damage response (DDR) is activated upon DNA damage generation to promote DNA repair and inhibit cell cycle progression in the presence of a lesion. Cellular senescence is a permanent cell cycle arrest characterized by persistent DDR activation. However, some reports suggest that DDR activati...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207795/ https://ncbi.nlm.nih.gov/pubmed/25340529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110969 |
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