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Stable Cellular Senescence Is Associated with Persistent DDR Activation

The DNA damage response (DDR) is activated upon DNA damage generation to promote DNA repair and inhibit cell cycle progression in the presence of a lesion. Cellular senescence is a permanent cell cycle arrest characterized by persistent DDR activation. However, some reports suggest that DDR activati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fumagalli, Marzia, Rossiello, Francesca, Mondello, Chiara, d’Adda di Fagagna, Fabrizio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207795/
https://ncbi.nlm.nih.gov/pubmed/25340529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110969
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