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Targeting the PI3K/AKT/mTOR pathway: potential for lung cancer treatment
The PI3K/AKT/mTOR pathway is commonly activated in non-small-cell lung cancer. It plays important roles in promoting oncogenesis in lung cancer and mediating resistance to EGF receptor tyrosine kinase inhibitors. Targeted agents against the components of this pathway are currently in development and...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203662/ https://ncbi.nlm.nih.gov/pubmed/25342981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/lmt.13.72 |
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