Glucocerebrosidase deficits in sporadic Parkinson disease

Parkinson disease (PD) is a progressive neurodegenerative movement disorder characterized pathologically by abnormal SNCA/α-synuclein protein inclusions in neurons. Impaired lysosomal autophagic degradation of cellular proteins is implicated in PD pathogenesis and progression. Heterozygous GBA mutat...

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Detaylı Bibliyografya
Asıl Yazarlar: Murphy, Karen E, Halliday, Glenda M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2014
Konular:
Autophagic Punctum
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203563/
https://ncbi.nlm.nih.gov/pubmed/24915553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29074
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