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Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T α-synuclein mutation
BACKGROUND: The A53T mutation in the α-synuclein gene causes autosomal-dominant Lewy body Parkinson's disease (PD). Cultured cell models have linked this mutation to increased cell macroautophagy, although evidence of enhanced macroautophagy in patients with this mutation has not been assessed....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3506995/ https://ncbi.nlm.nih.gov/pubmed/23210740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-1-2 |
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