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Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T α-synuclein mutation

BACKGROUND: The A53T mutation in the α-synuclein gene causes autosomal-dominant Lewy body Parkinson's disease (PD). Cultured cell models have linked this mutation to increased cell macroautophagy, although evidence of enhanced macroautophagy in patients with this mutation has not been assessed....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Huang, Yue, Chegini, Fariba, Chua, Germaine, Murphy, Karen, Gai, Weiping, Halliday, Glenda M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506995/
https://ncbi.nlm.nih.gov/pubmed/23210740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-1-2
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