Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T α-synuclein mutation

BACKGROUND: The A53T mutation in the α-synuclein gene causes autosomal-dominant Lewy body Parkinson's disease (PD). Cultured cell models have linked this mutation to increased cell macroautophagy, although evidence of enhanced macroautophagy in patients with this mutation has not been assessed....

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Detaylı Bibliyografya
Asıl Yazarlar: Huang, Yue, Chegini, Fariba, Chua, Germaine, Murphy, Karen, Gai, Weiping, Halliday, Glenda M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506995/
https://ncbi.nlm.nih.gov/pubmed/23210740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-1-2
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