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SREBF1 links lipogenesis to mitophagy and sporadic Parkinson disease

Mitochondrial quality control has an impact on many diseases, but intense research has focused on the action of 2 genes linked to heritable forms of Parkinson disease (PD), PINK1 and PARK2/parkin, which act in a common pathway to promote mitophagy. However, criticism has been raised that little evid...

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Bibliographic Details
Main Authors: Ivatt, Rachael M, Whitworth, Alexander J
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203527/
https://ncbi.nlm.nih.gov/pubmed/24991824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29642
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