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LC3 binds externalized cardiolipin on injured mitochondria to signal mitophagy in neurons: Implications for Parkinson disease

Mitophagy, or the selective clearance of mitochondria by autophagy, plays a key role in mitochondrial quality control. Due to their postmitotic nature and metabolic dependence on mitochondria, either insufficient or unchecked mitophagy is detrimental to neurons. To better understand signals that reg...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Autophagy
Prif Awduron: Chu, Charleen T, Bayır, Hülya, Kagan, Valerian E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396091/
https://ncbi.nlm.nih.gov/pubmed/24351649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27191
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