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mTORC1-dependent metabolic reprogramming is a prerequisite for Natural Killer cell effector function

The mammalian target of rapamcyin complex 1 (mTORC1) is a key regulator of cellular metabolism and also has fundamental roles in controlling immune responses. Emerging evidence suggests that these two functions of mTORC1 are integrally linked. However, little is known regarding mTORC1 function in co...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Donnelly, Raymond P., Loftus, Róisín M., Keating, Sinéad E., Liou, Kevin T., Biron, Christine A., Gardiner, Clair M., Finlay, David K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201970/
https://ncbi.nlm.nih.gov/pubmed/25261477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401558
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