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mTORC1-dependent metabolic reprogramming is a prerequisite for Natural Killer cell effector function

The mammalian target of rapamcyin complex 1 (mTORC1) is a key regulator of cellular metabolism and also has fundamental roles in controlling immune responses. Emerging evidence suggests that these two functions of mTORC1 are integrally linked. However, little is known regarding mTORC1 function in co...

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Bibliografiske detaljer
Main Authors: Donnelly, Raymond P., Loftus, Róisín M., Keating, Sinéad E., Liou, Kevin T., Biron, Christine A., Gardiner, Clair M., Finlay, David K.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201970/
https://ncbi.nlm.nih.gov/pubmed/25261477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401558
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