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Discrete functions of mTOR signaling in iNKT cell development and NKT17 fate decision
Invariant natural killer T (iNKT) cells have been recently classified into NKT1, NKT2 and NKT17 lineages with distinct transcription factor and cytokine profiles, but mechanisms underlying such fate decisions remain elusive. Here, we report crucial roles of mTOR signaling especially mTORC2 in iNKT c...
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Asıl Yazarlar: | , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2014
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201958/ https://ncbi.nlm.nih.gov/pubmed/25261481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402042 |
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