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Discrete functions of mTOR signaling in iNKT cell development and NKT17 fate decision

Invariant natural killer T (iNKT) cells have been recently classified into NKT1, NKT2 and NKT17 lineages with distinct transcription factor and cytokine profiles, but mechanisms underlying such fate decisions remain elusive. Here, we report crucial roles of mTOR signaling especially mTORC2 in iNKT c...

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Detalhes bibliográficos
Main Authors: Wei, Jun, Yang, Kai, Chi, Hongbo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201958/
https://ncbi.nlm.nih.gov/pubmed/25261481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402042
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