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Regulation and function of mTOR signalling in T cell fate decision
The evolutionary conserved kinase mTOR couples cell growth and metabolism to environmental inputs in eukaryotes. T cells depend on mTOR signalling to integrate immune signals and metabolic cues for their proper maintenance and activation. Under steady-state conditions, mTOR is actively controlled by...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417069/ https://ncbi.nlm.nih.gov/pubmed/22517423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3198 |
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