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mTOR signaling at the crossroads of environmental signals and T-cell fate decisions
The evolutionarily conserved serine/threonine kinase mTOR (mechanistic target of rapamycin) forms the distinct protein complexes mTORC1 and mTORC2 and integrates signals from the environment to coordinate downstream signaling events and various cellular processes. T cells rely on mTOR activity for t...
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| Publié dans: | Immunol Rev |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8101438/ https://ncbi.nlm.nih.gov/pubmed/32212344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12845 |
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