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mTOR signaling, Tregs and immune modulation

Foxp3(+) Tregs are central regulators of immune tolerance. As dysregulated Treg responses contribute to disease pathogenesis, novel approaches to target the immunomodulatory functions of Tregs are currently under investigation. mTORC1 and mTORC2 are therapeutic targets of interest. Recent studies re...

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Dades bibliogràfiques
Publicat a:Immunotherapy
Autors principals: Chapman, Nicole M, Chi, Hongbo
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291176/
https://ncbi.nlm.nih.gov/pubmed/25524385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.84
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