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mTOR signaling, Tregs and immune modulation
Foxp3(+) Tregs are central regulators of immune tolerance. As dysregulated Treg responses contribute to disease pathogenesis, novel approaches to target the immunomodulatory functions of Tregs are currently under investigation. mTORC1 and mTORC2 are therapeutic targets of interest. Recent studies re...
Sparad:
| I publikationen: | Immunotherapy |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291176/ https://ncbi.nlm.nih.gov/pubmed/25524385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.84 |
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