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A Roadmap for Natural Product Discovery Based on Large-Scale Genomics and Metabolomics
Actinobacteria encode a wealth of natural product biosynthetic gene clusters (NPGCs), whose systematic study is complicated by numerous repetitive motifs. By combining several metrics we developed a method for global classification of these gene clusters into families (GCFs) and analyzed the biosynt...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201863/ https://ncbi.nlm.nih.gov/pubmed/25262415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1659 |
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