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Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer
[Image: see text] For more than half a century the pharmaceutical industry has sifted through natural products produced by microbes, uncovering new scaffolds and fashioning them into a broad range of vital drugs. We sought a strategy to reinvigorate the discovery of natural products with distinctive...
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| Publié dans: | ACS Cent Sci |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical Society
2016
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4827660/ https://ncbi.nlm.nih.gov/pubmed/27163034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00331 |
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