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Discovery of the antibiotic phosacetamycin via a new mass spectrometry-based method for phosphonic acid detection

Naturally occurring phosphonates such as phosphinothricin (Glufosinate, a commercially used herbicide) and fosfomycin (Monurol, a clinically used antibiotic) have proved to be potent and useful biocides. Yet this class of natural products is still an under explored family of secondary metabolites. D...

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Detalhes bibliográficos
Main Authors: Evans, Bradley S., Zhao, Changming, Gao, Jiangtao, Evans, Courtney M., Ju, Kou-San, Doroghazi, James R., van der Donk, Wilfred A., Kelleher, Neil L., Metcalf, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657337/
https://ncbi.nlm.nih.gov/pubmed/23474169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400102t
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