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Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function
Eukaryotic cells license each DNA replication origin during G1 phase by assembling a prereplication complex that contains a Mcm2–7 (minichromosome maintenance proteins 2–7) double hexamer. During S phase, each Mcm2–7 hexamer forms the core of a replicative DNA helicase. However, the mechanisms of or...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201289/ https://ncbi.nlm.nih.gov/pubmed/25319829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.242313.114 |
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